AOFB Polyclonal Antibody, 100ul Gel & Buffers Neuronal PAS domain-containing protein 2

Neuronal PAS domain-containing protein 2 encoded by NPAS2 is a member of the basic helix-loop-helix (bHLH)-PAS family of transcription factors

The protein DCC netrin 1 receptor localizes to lipid rafts

activation occurs

Mutations in ACVR1B are associated with pituitary tumors

Several transcript variants exist for this gene| but the full-length natures of only two have been described to date

AOFB Polyclonal Antibody, 100ul Gel & Buffers Neuronal PAS domain-containing protein 2The protein encoded by this gene belongs to the flavin monoamine oxidase family. It is a enzyme located in the mitochondrial outer membrane. It catalyzes the oxidative deamination of biogenic and xenobiotic amines and plays an important role in the metabolism of neuroactive and vasoactive amines in the central nervous sysytem and peripheral tissues. This protein preferentially degrades benzylamine and phenylethylamine.