CDK3 Polyclonal Antibody, 50ul sgRNA Oligos Oncogenic fusions of the 5'

Oncogenic fusions of the 5' end of this gene with several different kinase genes occur in some neoplasias

Members of the connecdenn family| such as DENND1A| function as guanine nucleotide exchange factors (GEFs) for the early endosomal small GTPase RAB35 (MIM 604199) and bind to clathrin and clathrin adaptor protein-2 (AP2

and in derived large-cell lymphomas

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proteins interact with protein kinases and may serve as targets for activated GTPase

CDK3 Polyclonal Antibody, 50ul sgRNA Oligos Oncogenic fusions of the 5'This gene encodes a member of the cyclin dependent protein kinase family. The protein promotes entry into S phase, in part by activating members of the E2F family of transcription factors. The protein also associates with cyclin C and phosphorylates the retinoblastoma 1 protein to promote exit from G0.