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A20 Polyclonal Antibody, 100ul[BT-AP00064] Mechanical Pipette This enzyme is essential for

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A20 Polyclonal Antibody, 100ul[BT-AP00064] Mechanical Pipette This enzyme is essential forTNFAIP3 was identified as a gene whose expression is rapidly induced by the tumor necrosis factor (TNF). TNF alpha induced protein 3 encoded by TNFAIP3 is a zinc finger protein and ubiqitin editing enzyme, and has been shown to inhibit NF kappa B activation as well as TNF mediated apoptosis. The encoded protein, which has both ubiquitin ligase and deubiquitinase activities, is involved in the cytokine mediated immune and inflammatory responses.

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Description

This enzyme is essential for Helicobacter pylori adhesion to human gastric cancer cells

Aberrant binding to this subunit by proteins with expanded polyglutamine regions has been suggested as one of the pathogenetic mechanisms underlying a group of neurodegenerative disorders referred to as polyglutamine diseases

were discovered as mammalian homologs of the C

Contains 4 ANK repeats

Binding of these ligands to the receptor activates several signal transduction pathways

A20 Polyclonal Antibody, 100ul[BT-AP00064] Mechanical Pipette This enzyme is essential forTNFAIP3 was identified as a gene whose expression is rapidly induced by the tumor necrosis factor (TNF). TNF alpha induced protein 3 encoded by TNFAIP3 is a zinc finger protein and ubiqitin editing enzyme, and has been shown to inhibit NF kappa B activation as well as TNF mediated apoptosis. The encoded protein, which has both ubiquitin ligase and deubiquitinase activities, is involved in the cytokine mediated immune and inflammatory responses.

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