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p57(Phospho Thr310) Polyclonal Antibody, 50ul Plasma The protein encoded by this

SKU: 59430096515

4.2
EUR185.00 EUR217.00

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p57(Phospho Thr310) Polyclonal Antibody, 50ul Plasma The protein encoded by thisThis gene is imprinted, with preferential expression of the maternal allele. The encoded protein is a tight binding, strong inhibitor of several G1 cyclin Cdk complexes and a negative regulator of cell proliferation. Mutations in this gene are implicated in sporadic cancers and Beckwith Wiedemann syndorome, suggesting that this gene is a tumor suppressor candidate. Three transcript variants encoding two different isoforms have been found for this gene.

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Description

The protein encoded by this gene interacts with poly(A)-binding protein and with the cap-binding complex eIF4A

Interacts with MAFB

streptavidin-HRP labeled with horseradish peroxidase is added

As a scaffold protein may contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme

Mutations in this gene cause ovarian dysgenesis type 1

p57(Phospho Thr310) Polyclonal Antibody, 50ul Plasma The protein encoded by thisThis gene is imprinted, with preferential expression of the maternal allele. The encoded protein is a tight binding, strong inhibitor of several G1 cyclin Cdk complexes and a negative regulator of cell proliferation. Mutations in this gene are implicated in sporadic cancers and Beckwith Wiedemann syndorome, suggesting that this gene is a tumor suppressor candidate. Three transcript variants encoding two different isoforms have been found for this gene.

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