Phospho-BLNK (Y96) Polyclonal Antibody, 50ul Cell Biology involved in late-phase long-term potentiation

involved in late-phase long-term potentiation (L-LTP) maintenance at the Schaffer collateral-CA1 synapses

Related pseudogenes have been found on chromosomes 3 and 14

Inhibits the binding of prostaglandin F2-alpha (PGF2-alpha) to its specific FP receptor

This protein is not restricted to leukemic cells

This gene location is also the candidate region of two different neurologic diseases: early-onset parkinsonism (Waisman syndrome) and X-linked mental retardation (MRX3)

Phospho-BLNK (Y96) Polyclonal Antibody, 50ul Cell Biology involved in late-phase long-term potentiationBLNK encodes a cytoplasmic linker or adaptor protein that plays a critical role in B cell development. B cell linker bridges B cell receptor associated kinase activation with downstream signaling pathways, thereby affecting various biological functions. The phosphorylation of five tyrosine residues is necessary for this protein to nucleate distinct signaling effectors following B cell receptor activation. Mutations in this gene cause hypoglobulinemia