HES1 Polyclonal Antibody, 100ul General Lab Use A polymorphism in an intron

A polymorphism in an intron of this gene may be associated with longevity

Contains 1 peptidase S1 domain

Chromosomal translocations involving CREBBP have been associated with acute myeloid leukemia

where heterozygotes carrying an active paternal allele express the phenotype

SF3B3 encodes subunit 3 of the splicing factor 3b protein complex

HES1 Polyclonal Antibody, 100ul General Lab Use A polymorphism in an intronThis protein belongs to the basic helix loop helix family of transcription factors. It is a transcriptional repressor of genes that require a bHLH protein for their transcription. The protein has a particular type of basic domain that contains a helix interrupting protein that binds to the N box rather than the canonical E box.