Phospho-B23 (T199) Polyclonal Antibody, 100ul Cellular Function Assays This gene is expressed in

This gene is expressed in different carcinomas

Knockout studies in mice indicate that this gene is important for specification of paraxial mesoderm structures

it does not constitute the catalytic RING subunit in the DCX DET1-COP1 complex that negatively regulates JUN

Diseases associated with RASGRF1 include bleeding disorder

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Phospho-B23 (T199) Polyclonal Antibody, 100ul Cellular Function Assays This gene is expressed inNPM1 encodes a phosphoprotein which moves between the nucleus and the cytoplasm. The gene product is thought to be involved in several processes including regulation of the ARF p53 pathway. A number of genes are fusion partners have been characterized, in particular the anaplastic lymphoma kinase gene on chromosome 2. Mutations in this gene are associated with acute myeloid leukemia. More than a dozen pseudogenes of NPM1 have been identified.