Parkin Polyclonal Antibody, 20ul Cell Culture Plates with variations due to deletions

with variations due to deletions

It is localized to the cell membrane via a pleckstrin homology (PH) domain in the C-terminal region

IQ calmodulin-binding motif-containing protein 1 is thought to play a role in ciliary function

The protein encoded by DOK2 (docking protein 2)is constitutively tyrosine phosphorylated in hematopoietic progenitors isolated from chronic myelogenous leukemia (CML) patients in the chronic phase

inducing leukocyte migration and activation

Parkin Polyclonal Antibody, 20ul Cell Culture Plates with variations due to deletionsThe precise function of PARK2 is unknown; however, the encoded protein is a component of a multiprotein E3 ubiquitin ligase complex that mediates the targeting of substrate proteins for proteasomal degradation. Mutations in PARK2 are known to cause Parkinson disease and autosomal recessive juvenile Parkinson disease. Alternative splicing of PARK2 produces multiple transcript variants encoding distinct isoforms. Additional splice variants of PARK2 have