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Apaf-1 Polyclonal Antibody, 50ul Centrifugal Filter other factors

SKU: 59868985662

4.1
USD185.00 USD230.00

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Apaf-1 Polyclonal Antibody, 50ul Centrifugal Filter other factorsAPAF1 encodes a cytoplasmic protein that initiates apoptosis. Apoptotic protease activating factor 1 contains several copies of the WD 40 domain, a caspase recruitment domain (CARD), and an ATPase domain (NB ARC). Upon binding cytochrome c and dATP, this protein forms an oligomeric apoptosome. The apoptosome binds and cleaves caspase 9 preproprotein, releasing its mature, activated form. Activated caspase 9 stimulates the subsequent caspase cascade

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Description

other factors

Expression of ADCK2 inversely correlates with cellular viability

and inhibition of protein kinase C-mediated phosphorylation

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Apaf-1 Polyclonal Antibody, 50ul Centrifugal Filter other factorsAPAF1 encodes a cytoplasmic protein that initiates apoptosis. Apoptotic protease activating factor 1 contains several copies of the WD 40 domain, a caspase recruitment domain (CARD), and an ATPase domain (NB ARC). Upon binding cytochrome c and dATP, this protein forms an oligomeric apoptosome. The apoptosome binds and cleaves caspase 9 preproprotein, releasing its mature, activated form. Activated caspase 9 stimulates the subsequent caspase cascade

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