Max(Phospho Ser2) Polyclonal Antibody, 20ul Pipette Filler The encoded protein overcomes the

The encoded protein overcomes the mRNA export block caused by the presence of saturating amounts of CTE (constitutive transport element) RNA of type D retroviruses

EIF-2 is composed of three subunits

while the regulatory subunit is derived from a different gene located on chromosome 1p22-p21

and a cysteine-rich C-terminal domain

Multiple transcript variants encoding different isoforms have been characterized for this gene

Max(Phospho Ser2) Polyclonal Antibody, 20ul Pipette Filler The encoded protein overcomes theThe protein encoded by this gene is a member of the basic helix loop helix leucine zipper (bHLHZ) family of transcription factors. It is able to form homodimers and heterodimers with other family members, which include Mad, Mxi1 and Myc. Myc is an oncoprotein implicated in cell proliferation, differentiation and apoptosis. The homodimers and heterodimers compete for a common DNA target site (the E box) and rearrangement among these dimer forms