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WFKN2 Rabbit Polyclonal Antibody, 20ul Protein Modification The phosphodiesterase 10A encoded by

SKU: 60240125136

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WFKN2 Rabbit Polyclonal Antibody, 20ul Protein Modification The phosphodiesterase 10A encoded byThe WFIKKN1 protein contains a WAP domain follistatin domain immunoglobulin domain two tandem Kunitz domains and an NTR domain. This gene encodes a WFIKKN1 related protein which has the same domain organization as the WFIKKN1 protein. The WAP type follistatin type Kunitz type and NTR type protease inhibitory domains may control the action of multiple types of proteases.

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Description

The phosphodiesterase 10A encoded by PDE10A belongs to the cyclic nucleotide phosphodiesterase family

The encoded protein negatively regulates wingless/integrated signaling through interaction with the post synaptic density protein/ Drosophila disc large tumor suppressor/ zonula occludens-1 protein domain of Dishevelled| a scaffolding protein required for the stabilization of the transcriptional co-activator beta-catenin

CAV1 is a tumor suppressor gene candidate and a negative regulator of the Ras-p42/44 mitogen-activated kinase cascade

CXCL3 encodes a member of the CXC subfamily of chemokines

Regulates arterial blood pressure by stimulating vasodilation and reducing vascular smooth muscle and microvascular endothelial cell proliferation

WFKN2 Rabbit Polyclonal Antibody, 20ul Protein Modification The phosphodiesterase 10A encoded byThe WFIKKN1 protein contains a WAP domain follistatin domain immunoglobulin domain two tandem Kunitz domains and an NTR domain. This gene encodes a WFIKKN1 related protein which has the same domain organization as the WFIKKN1 protein. The WAP type follistatin type Kunitz type and NTR type protease inhibitory domains may control the action of multiple types of proteases.

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