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REV1 Polyclonal Antibody, 20ul Vessels overexpression is cytotoxic

SKU: 60250683176

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REV1 Polyclonal Antibody, 20ul Vessels overexpression is cytotoxicThis gene encodes a protein with similarity to the S. cerevisiae mutagenesis protein Rev1. The Rev1 proteins contain a BRCT domain, which is important in protein protein interactions. A suggested role for the human Rev1 like protein is as a scaffold that recruits DNA polymerases involved in translesion synthesis (TLS) of damaged DNA.

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Description

overexpression is cytotoxic

leading to phosphorylation and release of RPS6KB1 and binding of EIF4B to eIF-3

Guanine nucleotide exchange factor (GEF) for KRAS

and has RNA chaperone activity that may be involved in template switch

which are 96% homologous

REV1 Polyclonal Antibody, 20ul Vessels overexpression is cytotoxicThis gene encodes a protein with similarity to the S. cerevisiae mutagenesis protein Rev1. The Rev1 proteins contain a BRCT domain, which is important in protein protein interactions. A suggested role for the human Rev1 like protein is as a scaffold that recruits DNA polymerases involved in translesion synthesis (TLS) of damaged DNA.

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