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PBIP1 Rabbit Polyclonal Antibody, 20ul Cell Dissociation Peroxidases of the peroxiredoxin family

SKU: 60316894191

4.3
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PBIP1 Rabbit Polyclonal Antibody, 20ul Cell Dissociation Peroxidases of the peroxiredoxin familyThe protein encoded by this gene interacts with the PBX1 homeodomain protein inhibiting its transcriptional activation potential by preventing its binding to DNA. The encoded protein which is primarily cytosolic but can shuttle to the nucleus also can interact with estrogen receptors alpha and beta and promote the proliferation of breast cancer brain tumors and lung cancer. Several transcript variants encoding different isoforms have been found for

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Description

Peroxidases of the peroxiredoxin family reduce hydrogen peroxide and alkyl hydroperoxides to water and alcohol with the use of reducing equivalents derived from thiol-containing donor molecules

The functional enzyme is thought to be a homodimer which uses FAD as a cofactor

pancreas and gastric carcinoma cell lines

The import of proteins with a nuclear localization signal (NLS) is accomplished by recognition of one or more clusters of basic amino acids by the importin-alpha/beta complex

that is involved in transcription initiation and DNA repair

PBIP1 Rabbit Polyclonal Antibody, 20ul Cell Dissociation Peroxidases of the peroxiredoxin familyThe protein encoded by this gene interacts with the PBX1 homeodomain protein inhibiting its transcriptional activation potential by preventing its binding to DNA. The encoded protein which is primarily cytosolic but can shuttle to the nucleus also can interact with estrogen receptors alpha and beta and promote the proliferation of breast cancer brain tumors and lung cancer. Several transcript variants encoding different isoforms have been found for

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