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Phospho-14-3-3 Theta/Tau (S232) Polyclonal Antibody, 100ul Petri Dishes Mutations in this gene have

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Phospho-14-3-3 Theta/Tau (S232) Polyclonal Antibody, 100ul Petri Dishes Mutations in this gene haveThe protein encoded by PLN (phospholamban) is found as a pentamer and is a major substrate for the cAMP dependent protein kinase in cardiac muscle. The encoded protein is an inhibitor of cardiac muscle sarcoplasmic reticulum Ca(2+) ATPase in the unphosphorylated state, but inhibition is relieved upon phosphorylation of the protein. The subsequent activation of the Ca(2+) pump leads to enhanced muscle relaxation rates, thereby contributing to the

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Description

Mutations in this gene have been associated with a predisposition to atypical hemolytic uremic syndrome

|Acute phase-regulated receptor involved in clearance and endocytosis of hemoglobin/haptoglobin complexes by macrophages and may thereby protect tissues from free hemoglobin-mediated oxidative damage

resulting in stimulation of polymerase activity by enhancing DNA binding and processivity

which regulates its rapid exchange between the plasma membrane and the Golgi apparatus

This gene is the human homolog of mouse BMP-2-inducible kinase

Phospho-14-3-3 Theta/Tau (S232) Polyclonal Antibody, 100ul Petri Dishes Mutations in this gene haveThe protein encoded by PLN (phospholamban) is found as a pentamer and is a major substrate for the cAMP dependent protein kinase in cardiac muscle. The encoded protein is an inhibitor of cardiac muscle sarcoplasmic reticulum Ca(2+) ATPase in the unphosphorylated state, but inhibition is relieved upon phosphorylation of the protein. The subsequent activation of the Ca(2+) pump leads to enhanced muscle relaxation rates, thereby contributing to the

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