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MBP-Tag Polyclonal Antibody, 20ul Reagent Reservoirs Upon activation by elevated cAMP

SKU: 60615124510

4.0
USD111.00 USD157.00

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MBP-Tag Polyclonal Antibody, 20ul Reagent Reservoirs Upon activation by elevated cAMPMaltose binding protein (MBP) is the 370 amino acid product of the E. coli mal E gene. MBP is a useful affinity tag that can increase the expression level and solubility of the resulting tagged protein. The MBP tag also promotes proper folding of the attached protein. Plasmid vectors have been constructed utilizing the MBP domain that allow the synthesis of high levels of MBP fusion proteins that can be purified in a one step procedure by affinity

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Description

Upon activation by elevated cAMP or calcium

Mutations in this gene cause X-linked agammaglobulinemia type 1| which is an immunodeficiency characterized by the failure to produce mature B lymphocytes| and associated with a failure of Ig heavy chain rearrangement

|pharmaceutical:A constitutively active FOXO4 mutant where phosphorylation sites Thr-32| Ser-187 and Ser-262 have been mutated to alanine may have therapeutic potential in ERBB2/HER2-overexpressing cancers as it inhibits ERBB2-mediated cell survival| transformation and tumorigenicity

Required to support proliferation and self-renewal of proximal germ cells in males only

homoserine

MBP-Tag Polyclonal Antibody, 20ul Reagent Reservoirs Upon activation by elevated cAMPMaltose binding protein (MBP) is the 370 amino acid product of the E. coli mal E gene. MBP is a useful affinity tag that can increase the expression level and solubility of the resulting tagged protein. The MBP tag also promotes proper folding of the attached protein. Plasmid vectors have been constructed utilizing the MBP domain that allow the synthesis of high levels of MBP fusion proteins that can be purified in a one step procedure by affinity

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