ALMS1 Polyclonal Antibody, 100ul Drug Development and Evaluation The N-terminal region is required

The N-terminal region is required for nuclear localization and the C-terminal region mediates transcriptional activity

This gene is a member of the WNT gene family

Take the risk and see the benefits for yourself

Members of this family have identical structural organization that consists of an N-terminal coiled-coil motif| a central Sec7 domain| and a C-terminal pleckstrin homology (PH) domain

at least composed of ATXN7

ALMS1 Polyclonal Antibody, 100ul Drug Development and Evaluation The N-terminal region is requiredALMS1 encodes a protein containing a large tandem repeat domain as well as additional low complexity regions. The encoded protein (ALMS1, centrosome and basal body associated protein) functions in microtubule organization, particularly in the formation and maintanance of cilia. Mutations ALMS1 cause Alstrom syndrome. There is a pseudogene for ALMS1 located adjacent in the same region of chromosome 2. Alternative splice variants have been described but