Hox-A7 Polyclonal Antibody, 50ul General Lab Use Mutations in this gene have

Mutations in this gene have been associated with myoclonic epilepsy of Lafora

The gene encoding this enzyme functions as the target for several anticancer agents and a variety of mutations in this gene have been associated with the development of drug resistance

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Defects in this gene are associated with Fuchs endothelial corneal dystrophy and posterior polymorphous corneal dystrophy type 2

and prevents the activation of the CDK kinases

Hox-A7 Polyclonal Antibody, 50ul General Lab Use Mutations in this gene haveIn vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. HOXA7 is part of the A cluster on chromosome 7 and encodes a DNA binding transcription factor which may regulate gene expression, morphogenesis and differentiation. For example, Homeobox