UBE4A Polyclonal Antibody, 100ul Cellular Function Assays The protein encoded by this

The protein encoded by this gene is a membrane protein found at the tight junctions between epithelial cells

It possesses histone deacetylase activity and represses transcription when tethered to a promoter

which are important in RNA binding and are known to be involved in RNA synthesis and metabolism

Undetectable in other tissues

MIM 607393)| CTR9 (MIM 609366)| and PAF1 (MIM 610506) form the PAF protein complex that associates with the RNA polymerase II subunit POLR2A (MIM 180660) and with a histone methyltransferase complex (Rozenblatt-Rosen et al

UBE4A Polyclonal Antibody, 100ul Cellular Function Assays The protein encoded by thisUBE4A encodes a member of the U box ubiquitin ligase family. The ubiquitination factor E4A is involved in multiubiquitin chain assembly and plays a critical role in chromosome condensation and separation through the polyubiquitination of securin. Autoantibodies against the encoded protein may be markers for scleroderma and Crohn's disease. A pseudogene of this gene is located on the long arm of chromosome 3. Alternatively spliced transcript variants