CD57 Polyclonal Antibody, 50ul[BT-AP02095] RNA Synthesis The protein encoded by TSG101

The protein encoded by TSG101 (tumor susceptibility 101) belongs to a group of apparently inactive homologs of ubiquitin-conjugating enzymes

and certain facial and developmental defects

Polymorphisms in the gene encoding this protein are associated with impaired transporter function

which leads to the loss in membrane potential and the release of cytochrome c

DNA damage checkpoint signaling

CD57 Polyclonal Antibody, 50ul[BT-AP02095] RNA Synthesis The protein encoded by TSG101COL7A1 encodes the alpha chain of type VII collagen. The type VII collagen fibril, composed of three identical alpha collagen chains, is restricted to the basement zone beneath stratified squamous epithelia. It functions as an anchoring fibril between the external epithelia and the underlying stroma. Mutations in this gene are associated with all forms of dystrophic epidermolysis bullosa. In the absence of mutations, however, an acquired form of this