CSN7A Polyclonal Antibody, 20ul Pathway and Network Analysis Different polymorphic forms

Different polymorphic forms

Mitochondrial translation is crucial for maintaining mitochondrial function and mutations in this system lead to a breakdown in the respiratory chain-oxidative phosphorylation system and to impaired maintenance of mitochondrial DNA

Mutations in this gene are associated with xeroderma pigmentosum complementation group A

Alternatively spliced transcript variants encoding the same isoform have been described

including RAB26

CSN7A Polyclonal Antibody, 20ul Pathway and Network Analysis Different polymorphic formsThis gene encodes a component of the COP9 signalosome, an evolutionarily conserved multi subunit protease that regulates the activity of the ubiquitin conjugation pathway. Alternatively spliced transcript variants that encode the same protein have been described.