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Plakophilin 2 Polyclonal Antibody, 100ul Serological Pipets The protein encoded by this

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Plakophilin 2 Polyclonal Antibody, 100ul Serological Pipets The protein encoded by thisPKP2 encodes a member of the arm repeat (armadillo) and plakophilin gene families. Plakophilin proteins contain numerous armadillo repeats, localize to cell desmosomes and nuclei, and participate in linking cadherins to intermediate filaments in the cytoskeleton. PKP2 product may regulate the signaling activity of beta catenin. Two alternately spliced transcripts encoding two protein isoforms have been identified. A processed pseudogene with high

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Description

The protein encoded by this gene is a caspase-3 substrate that plays a role in regulating microfilament and cell shape changes during apoptosis

Consequently

Some of these isoforms are beta subunits

This gene encodes a member of the Nedd4 family of HECT domain E3 ubiquitin ligases

in tumor masses and invasive epithelium

Plakophilin 2 Polyclonal Antibody, 100ul Serological Pipets The protein encoded by thisPKP2 encodes a member of the arm repeat (armadillo) and plakophilin gene families. Plakophilin proteins contain numerous armadillo repeats, localize to cell desmosomes and nuclei, and participate in linking cadherins to intermediate filaments in the cytoskeleton. PKP2 product may regulate the signaling activity of beta catenin. Two alternately spliced transcripts encoding two protein isoforms have been identified. A processed pseudogene with high

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