NMBR Polyclonal Antibody, 50ul[BT-AP06070] Drug Development and Evaluation with similarity to the globular

with similarity to the globular (non-collagen-like) domain of complement component C1qB

The mouse gene is located in double minute (DM) chromatin particles

The encoded protein associates with actin-based cytoskeletal structures and may play a role in multiple processes including hair cell stereocilia formation| myoblast proliferation and glomerular podocyte and endothelial cell maintenance

7-transmembrane receptor

The main structural proteins of mammalian hair fiber are the hair keratins (see MIM 601077) and the keratin-associated proteins (KAPs)| which form a rigid and resistant hair shaft through extensive disulfide bond crosslinking with the abundant cysteines of hair keratins (Shimomura et al

NMBR Polyclonal Antibody, 50ul[BT-AP06070] Drug Development and Evaluation with similarity to the globularNMBR encodes a 7 transmembrane G protein coupled receptor that binds neuromedin B, which is a growth factor and mitogen for gastrointestinal epithelial tissue and for normal and neoplastic lung. This receptor may play a role in smooth muscle contraction, neuronal responses, and the regulation of cell growth. Antagonists of this receptor have a potential therapeutic use in inhibiting tumor cell growth. Polymorphisms in NMBR may be associated with a