Rb(Phospho Ser612) Polyclonal Antibody, 50ul sgRNA customized design Diseases associated with ZDHHC2 include

Diseases associated with ZDHHC2 include hepatocellular carcinoma and locked-in syndrome

Activating transcription factor 2 has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions

a subset of which do not have known ligands and are referred to as orphan nuclear receptors

It is a member of the secretoglobin gene family and forms a heterodimer with lipophilin B

This member is a gamma subunit functioning as a modulatory molecule

Rb(Phospho Ser612) Polyclonal Antibody, 50ul sgRNA customized design Diseases associated with ZDHHC2 includeThe protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.