PARP-1 (Acetyl-K521) Polyclonal Antibody, 20ul Recombinant Ab Production Belongs to the cyclic nucleotide

Belongs to the cyclic nucleotide phosphodiesterase family

Two nearly identical copies of this gene are found in a palindromic region on chromosome Y

a subset of spliceosomal snRNAs are exported from the nucleus after transcription

the gene encoding VWA5A maps to human chromosome 11q24

Mutations in this gene are associated with Mitchell-Riley syndrome| which is characterized by neonatal diabetes with pancreatic hypoplasia| duodenal and jejunal atresia| and gall bladder agenesis

PARP-1 (Acetyl-K521) Polyclonal Antibody, 20ul Recombinant Ab Production Belongs to the cyclic nucleotideThis gene encodes a chromatin associated enzyme, poly(ADP ribosyl)transferase, which modifies various nuclear proteins by poly(ADP ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be