SHIP2(Phospho-Tyr986/987) Rabbit Polyclonal Antibody, 50ul Gene Editing Patients with mutations in this

Patients with mutations in this gene have altered levels of sphingolipid and phospholipids in the brain

Opioid binding protein/cell adhesion molecule like is proteolytically processed to generate the mature protein

The enzymatic activity is regulated by a phosphorylation/dephosphorylation cycle

The encoded cytosolic protein and mitochondrial glycerol-3-phosphate dehydrogenase also form a glycerol phosphate shuttle that facilitates the transfer of reducing equivalents from the cytosol to mitochondria

with the most highly conserved domain consisting of seven contiguous residues that constitute the hydrophobic binding site for medium- and long-chain acyl-Coenzyme A esters

SHIP2(Phospho-Tyr986/987) Rabbit Polyclonal Antibody, 50ul Gene Editing Patients with mutations in thisThe protein encoded by this gene is an SH2 containing 5' inositol phosphatase that is involved in the regulation of insulin function. The encoded protein also plays a role in the regulation of epidermal growth factor receptor turnover and actin remodelling. Additionally this gene supports metastatic growth in breast cancer and is a valuable biomarker for breast cancer.