AIRE-1 Polyclonal Antibody, 50ul[BT-AP00311] DNA Synthesis Mutations in MT-CO1 have been

Mutations in MT-CO1 have been associated with Leber's hereditary optic neuropathy (LHON)

This gene encodes a member of the NeuroD family of basic helix-loop-helix (bHLH) transcription factors

The primary sequences of the three human mitochondria

The protein encoded by this gene is involved in processes including neurite growth and migration

which are involved in microtubule assembly and important for neurogenesis

AIRE-1 Polyclonal Antibody, 50ul[BT-AP00311] DNA Synthesis Mutations in MT-CO1 have beenAIRE encodes a transcriptional regulator that forms nuclear bodies and interacts with the transcriptional coactivator CREB binding protein. The autoimmune regulator plays an important role in immunity by regulating the expression of autoantigens and negative selection of autoreactive T cells in the thymus. Mutations in this gene cause the rare autosomal recessive systemic autoimmune disease termed autoimmune polyendocrinopathy with candidiasis and