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RASL2 Polyclonal Antibody, 50ul Digital Burette forms the DNA polymerase alpha

SKU: 62436276401

4.2
SEK185.00 SEK220.00

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RASL2 Polyclonal Antibody, 50ul Digital Burette forms the DNA polymerase alphaThis gene encodes a member of the GAP1 family of GTPase activating proteins that suppresses the Ras mitogen activated protein kinase pathway in response to Ca(2+). Stimuli that increase intracellular Ca(2+) levels result in the translocation of this protein to the plasma membrane, where it activates Ras GTPase activity. Consequently, Ras is converted from the active GTP bound state to the inactive GDP bound state and no longer activates downstream

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Description

forms the DNA polymerase alpha complex

Polymorphisms in this gene have been implicated in modifying risk of Parkinson disease

This reaction uses calcium as a cofactor and plays an important role in the intracellular transduction of many extracellular signals

The activation is rapid and specific

Able to bind iron-bound LCN2 (holo-24p3)

RASL2 Polyclonal Antibody, 50ul Digital Burette forms the DNA polymerase alphaThis gene encodes a member of the GAP1 family of GTPase activating proteins that suppresses the Ras mitogen activated protein kinase pathway in response to Ca(2+). Stimuli that increase intracellular Ca(2+) levels result in the translocation of this protein to the plasma membrane, where it activates Ras GTPase activity. Consequently, Ras is converted from the active GTP bound state to the inactive GDP bound state and no longer activates downstream

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