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HNF-4 Alpha/Gamma Polyclonal Antibody, 100ul[BT-AP04160] Immunoassays This transporter is the primary

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HNF-4 Alpha/Gamma Polyclonal Antibody, 100ul[BT-AP04160] Immunoassays This transporter is the primaryHepatocyte nuclear factor 4 alpha encoded by HNF4A is a nuclear transcription factor which binds DNA as a homodimer. The encoded protein controls the expression of several genes, including hepatocyte nuclear factor 1 alpha, a transcription factor which regulates the expression of several hepatic genes. This gene may play a role in development of the liver, kidney, and intestines. Mutations in this gene have been associated with monogenic autosomal

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Description

This transporter is the primary mechanism for uptake of intestinal bile acids by apical cells in the distal ileum

which are often found in proteins involved in signal transduction or membrane trafficking

The TRRAP/TIP60 complex acetylates nucleosomal histones important for transcriptional regulation

this enzyme cleaves alpha 1-proteinase inhibitor but weakly degrades structural proteins of the extracellular matrix

The protein encoded by HIF3A (hypoxia inducible factor 3 alpha subunit) is the alpha-3 subunit of one of several alpha/beta-subunit heterodimeric transcription factors that regulate many adaptive responses to low oxygen tension (hypoxia)

HNF-4 Alpha/Gamma Polyclonal Antibody, 100ul[BT-AP04160] Immunoassays This transporter is the primaryHepatocyte nuclear factor 4 alpha encoded by HNF4A is a nuclear transcription factor which binds DNA as a homodimer. The encoded protein controls the expression of several genes, including hepatocyte nuclear factor 1 alpha, a transcription factor which regulates the expression of several hepatic genes. This gene may play a role in development of the liver, kidney, and intestines. Mutations in this gene have been associated with monogenic autosomal

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