IGF-I Receptor beta(Phospho-Tyr980) Rabbit Polyclonal Antibody, 100ul Protein Post-translational Modification while the bulk pack of

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Aberrant expression of the gene is associated with cancer proliferation in numerous tissues

FGFR-3 is also encoded on chromosome 4 and has been associated with thanatophoric dwarfism

This protein also shuttles through the nucleus and may function as a transcriptional co-activator

elevated intracellular calcium levels induce a conformational change that exposes the myristoyl group

IGF-I Receptor beta(Phospho-Tyr980) Rabbit Polyclonal Antibody, 100ul Protein Post-translational Modification while the bulk pack ofThis receptor binds insulin like growth factor with a high affinity. It has tyrosine kinase activity. The insulin like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms have