GPR3 Polyclonal Antibody, 50ul Thermal Control Several alternatively spliced transcript variants

Several alternatively spliced transcript variants encoding different isoforms have been identified

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Disruptions in this gene are thought to be associated with neural tube defects

and trigger apoptosis of various tumor cells

Contains 6 LRR (leucine-rich) repeats

GPR3 Polyclonal Antibody, 50ul Thermal Control Several alternatively spliced transcript variantsThis gene is a member of the G protein coupled receptor family and is found in the cell membrane. G protein coupled receptors, characterized by a seven transmembrane domain motif, are involved in translating outside signals into G protein mediated intracellular effects. The encoded protein activates adenylate cyclase and modulates amyloid beta production in a mouse model, suggesting that it may play a role in Alzheimer's disease.