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11 Beta-HSD1 Polyclonal Antibody, 100ul[BT-AP00001] Enzyme Activity Assays May function as scaffolding or

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11 Beta-HSD1 Polyclonal Antibody, 100ul[BT-AP00001] Enzyme Activity Assays May function as scaffolding orHydroxysteroid 11 beta dehydrogenase 1 encoded by HSD11B1 is a microsomal enzyme that catalyzes the conversion of the stress hormone cortisol to the inactive metabolite cortisone. In addition, the encoded protein can catalyze the reverse reaction, the conversion of cortisone to cortisol. Too much cortisol can lead to central obesity, and a particular variation in HSD11B1 has been associated with obesity and insulin resistance in children. Mutations in

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Description

May function as scaffolding or signaling protein

it is normally found in the nucleus except during mitosis

and is involved in IL-31 signaling via activation of STAT-3 and STAT-5

This gene encodes a member of the suppressor of hairless protein family

Myosin| a structural component of muscle| consists of two heavy chains and four light chains

11 Beta-HSD1 Polyclonal Antibody, 100ul[BT-AP00001] Enzyme Activity Assays May function as scaffolding orHydroxysteroid 11 beta dehydrogenase 1 encoded by HSD11B1 is a microsomal enzyme that catalyzes the conversion of the stress hormone cortisol to the inactive metabolite cortisone. In addition, the encoded protein can catalyze the reverse reaction, the conversion of cortisone to cortisol. Too much cortisol can lead to central obesity, and a particular variation in HSD11B1 has been associated with obesity and insulin resistance in children. Mutations in

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