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TBC1D4(Phospho Thr642) Polyclonal Antibody, 50ul Capsule Filter NBPF4 is a member of

SKU: 63283816719

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TBC1D4(Phospho Thr642) Polyclonal Antibody, 50ul Capsule Filter NBPF4 is a member ofThis gene is a member of the Tre 2 BUB2 CDC16 domain family. The protein encoded by this gene is a Rab GTPase activating protein and contains two phopshotyrosine binding domains (PTB1 and PTB2) a calmodulin binding domain (CBD) a Rab GTPase domain and multiple AKT phosphomotifs. This protein is thought to play an important role in glucose homeostasis by regulating the insulin dependent trafficking of the glucose transporter 4 (GLUT4) important for

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Description

NBPF4 is a member of the neuroblastoma breakpoint family (NBPF) which consists of dozens of recently duplicated genes primarily located in segmental duplications on human chromosome 1

This gene is a tumor suppressor and encodes a protein that binds to the eukaryotic translation initiation factor 4A1 and inhibits its function by preventing RNA binding

NFKBIA encodes a member of the NF-kappa-B inhibitor family

Studies in mice also suggest that this kinase may also regulate neuronal functions and correlate fear-induced conflict behavior after stress

mutations in this gene

TBC1D4(Phospho Thr642) Polyclonal Antibody, 50ul Capsule Filter NBPF4 is a member ofThis gene is a member of the Tre 2 BUB2 CDC16 domain family. The protein encoded by this gene is a Rab GTPase activating protein and contains two phopshotyrosine binding domains (PTB1 and PTB2) a calmodulin binding domain (CBD) a Rab GTPase domain and multiple AKT phosphomotifs. This protein is thought to play an important role in glucose homeostasis by regulating the insulin dependent trafficking of the glucose transporter 4 (GLUT4) important for

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