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IRAK-1 Polyclonal Antibody, 50ul[BT-AP04619] Adeno-associated Virus Packaging Probably involved in formation of

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IRAK-1 Polyclonal Antibody, 50ul[BT-AP04619] Adeno-associated Virus Packaging Probably involved in formation ofIRAK1 encodes the interleukin 1 receptor associated kinase 1, one of two putative serine threonine kinases that become associated with the interleukin 1 receptor (IL1R) upon stimulation. This gene is partially responsible for IL1 induced upregulation of the transcription factor NF kappa B. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

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Description

Probably involved in formation of autophagosomal vacuoles (autophagosomes)

Naturally occuring readthrough transcription occurs between this locus and the downstream GNMT (glycine N-methyltransferase) gene and is represented with GeneID:107080644

CPT I is the key enzyme in the carnitine-dependent transport across the mitochondrial inner membrane and its deficiency results in a decreased rate of fatty acid beta-oxidation

Co-transcription of NME1 and the neighboring downstream gene (NME2) generates naturally-occurring transcripts (NME1-NME2)

It may play a role in T-cell-B-cell interactions

IRAK-1 Polyclonal Antibody, 50ul[BT-AP04619] Adeno-associated Virus Packaging Probably involved in formation ofIRAK1 encodes the interleukin 1 receptor associated kinase 1, one of two putative serine threonine kinases that become associated with the interleukin 1 receptor (IL1R) upon stimulation. This gene is partially responsible for IL1 induced upregulation of the transcription factor NF kappa B. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

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