KRA42 Rabbit Polyclonal Antibody, 100ul Palm Micro Centrifuges Mutations in several of the

Mutations in several of the genes that map to chromosome 22 are involved in the development of Phelan-McDermid syndrome

ARHGAP1 encodes a member of a large family of proteins that activate Rho-type guanosine triphosphate (GTP) metabolizing enzymes

Four members of this family have been clearly implicated in tumorigenesis via their involvement in chromosomal translocations in lymphoid tumors: MYC

as well as for its stimulation of basic fibroblast growth factor expression

and the TFTC (TATA-binding-protein-free TAF(II)-containing complex)

KRA42 Rabbit Polyclonal Antibody, 100ul Palm Micro Centrifuges Mutations in several of theThis protein is a member of the keratin associated protein (KAP) family. The KAP proteins form a matrix of keratin intermediate filaments which contribute to the structure of hair fibers. KAP family members appear to have unique family specific amino and carboxyl terminal regions and are subdivided into three multi gene families according to amino acid composition: the high sulfur the ultrahigh sulfur and the high tyrosine glycine KAPs. This protein