Calreticulin Rabbit Polyclonal Antibody, 100ul Variant Libraries and thus may transduce signals

and thus may transduce signals for cell survival and proliferation

Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression

mediate PLC-beta-2 activation and lead to the gating of TRPM5

which may modulate the efficiency of insulin signal transduction

it suppresses the activation of MAP kinase by oncogenic ras in extracts of Xenopus oocytes

Calreticulin Rabbit Polyclonal Antibody, 100ul Variant Libraries and thus may transduce signalsCalreticulin is a multifunctional protein that acts as a major Ca(2+) binding (storage) protein in the lumen of the endoplasmic reticulum. It is also found in the nucleus, suggesting that it may have a role in transcription regulation. Calreticulin binds to the synthetic peptide KLGFFKR, which is almost identical to an amino acid sequence in the DNA binding domain of the superfamily of nuclear receptors. Calreticulin binds to antibodies in certain