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SnoN Polyclonal Antibody, 100ul Yeast Expression The ubiquitin associated domain is

SKU: 6337598622

4.1
DKK123.75 DKK157.75

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SnoN Polyclonal Antibody, 100ul Yeast Expression The ubiquitin associated domain isSki like protein encoded by SKIL is a component of the SMAD pathway, which regulates cell growth and differentiation through transforming growth factor beta (TGFB). In the absence of ligand, the encoded protein binds to the promoter region of TGFB responsive genes and recruits a nuclear repressor complex. TGFB signaling causes SMAD3 to enter the nucleus and degrade this protein, allowing these genes to be activated. Four transcript variants encoding

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Description

The ubiquitin associated domain is thought to be a non-covalent ubiquitin binding domain consisting of a compact three helix bundle

predominantly under the influence of IL12

This complex binds to the promoters of snRNA genes transcribed by either RNA polymerase II or III and recruits other regulatory factors to activate snRNA gene transcription

a coiled-coil (leucine zipper) motif

an actin-binding domain

SnoN Polyclonal Antibody, 100ul Yeast Expression The ubiquitin associated domain isSki like protein encoded by SKIL is a component of the SMAD pathway, which regulates cell growth and differentiation through transforming growth factor beta (TGFB). In the absence of ligand, the encoded protein binds to the promoter region of TGFB responsive genes and recruits a nuclear repressor complex. TGFB signaling causes SMAD3 to enter the nucleus and degrade this protein, allowing these genes to be activated. Four transcript variants encoding

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