BMP-8A Polyclonal Antibody, 50ul[BT-AP14462] Pathway and Network Analysis a metalloproteinase domain

a metalloproteinase domain

The protein encoded by this gene is a basic leucine zipper (bZIP) transcription factor that plays an important role in the regulation of lineage-specific hematopoiesis

Mutations in this gene result in pontocerebellar hypoplasia type 2

Sporadic and familial mutations in this gene result in paragangliomas and pheochromocytoma

|Contains 9 SRCR domains

BMP-8A Polyclonal Antibody, 50ul[BT-AP14462] Pathway and Network Analysis a metalloproteinase domainThis gene encodes a secreted ligand of the TGF beta (transforming growth factor beta) superfamily of proteins. Ligands of this family bind various TGF beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide linked homodimer. This protein may play a role in development of the reproductive