Beclin-1 Monoclonal Antibody, 100ul[BT-MCA0208] Enzymes & Activity Assays |PTM:Phosphorylation of Thr-145 by Akt

|PTM:Phosphorylation of Thr-145 by Akt or of Ser-146 by PKC impairs binding to PCNA

another member of the neuregulin family of ligands

Several pseudogenes of this gene are found on chromosome 19

Acts as a nucleolar anchoring protein for DDX47

contains a binding site for eIF4E at the N-terminus

Beclin-1 Monoclonal Antibody, 100ul[BT-MCA0208] Enzymes & Activity Assays |PTM:Phosphorylation of Thr-145 by AktThis gene encodes a protein that regulates autophagy, a catabolic process of degradation induced by starvation. The encoded protein is a component of the phosphatidylinositol 3 kinase (PI3K) complex which mediates vesicle trafficking processes. This protein is thought to play a role in multiple cellular processes, including tumorigenesis, neurodegeneration and apoptosis. Alternative splicing results in multiple transcript variants.