Collagen IV alpha2 (Cleaved-Ser1485) Rabbit Polyclonal Antibody, 100ul Lysosome The main features of this

The main features of this syndrome involve retinal abnormalities

The secreted protein acidic and cysteine rich is required for the collagen in bone to become calcified but is also involved in extracellular matrix synthesis and promotion of changes to cell shape

which may mediate insulin signals to the actin cytoskeleton

and so is not thought to be a cell-cell adhesion glycoprotein

Two chains of the factor are held together by 1 or more disulfide bonds

Collagen IV alpha2 (Cleaved-Ser1485) Rabbit Polyclonal Antibody, 100ul Lysosome The main features of thisAlpha chains of type IV collagen have a non collagenous domain (NC1) at their C terminus frequent interruptions of the G X Y repeats in the long central triple helical domain (which may cause flexibility in the triple helix) and a short N terminal triple helical 7S domain. Type IV collagen is the major structural component of glomerular basement membranes (GBM) forming a 'chicken wire' meshwork together with laminins proteoglycans and entactin