RUVB1 Rabbit Polyclonal Antibody, 100ul Sampling Tubes When bound to ligands

When bound to ligands

and is therefore a potential tumor suppressor

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May act by blocking phosphorylation of NFKBIB and mediating cytoplasmic retention of p65/RELA NF-kappa-B subunit

The encoded protein is thought to be a glycosyltransferase and could play a role in brain development

RUVB1 Rabbit Polyclonal Antibody, 100ul Sampling Tubes When bound to ligandsThis gene encodes a protein that has both DNA dependent ATPase and DNA helicase activities and belongs to the ATPases associated with diverse cellular activities (AAA+) protein family. The encoded protein associates with several multisubunit transcriptional complexes and with protein complexes involved in both ATP dependent remodeling and histone modification. Alternate splicing results in multiple transcript variants.