RPA40 Polyclonal Antibody, 100ul Culture Tubes Studies on the mouse homolog

Studies on the mouse homolog suggested a function in bone morphogenesis and limb development through the sonic hedgehog (SHH) signaling pathway

The DHHC domain is required for palmitoyltransferase activity

Multiple alternatively spliced transcript variants have been observed that encode distinct proteins

SMG7 encodes protein SMG7 that is essential for nonsense-mediated mRNA decay (NMD)

BTB/POZ proteins are involved in several cellular processes including proliferation

RPA40 Polyclonal Antibody, 100ul Culture Tubes Studies on the mouse homologThe protein encoded by POLR1C (RNA polymerase I subunit C) is a subunit of both RNA polymerase I and RNA polymerase III complexes. The encoded protein is part of the Pol core element. Mutations in POLR1C have been associated with Treacher Collins syndrome (TCS) and hypomyelinating leukodystrophy 11. Alternative splicing results in multiple transcript variants.