PS-1 Polyclonal Antibody, 20ul Cell Culture Flasks and thus may contribute to

and thus may contribute to tumorigenesis

The ADP ribosylation factor GTPase activating protein 3 encoded by ARFGAP3 is a GTPase-activating protein (GAP) that associates with the Golgi apparatus and regulates the early secretory pathway of proteins

The encoded protein is involved in the regulation of the microtubule filament system by destabilizing microtubules

CCL4 attracts a variety of immune cells to sites of microbial infection as well as to other pathologic inflammation such as allergic asthma and ischemic myocardium

Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms

PS-1 Polyclonal Antibody, 20ul Cell Culture Flasks and thus may contribute toAlzheimer's disease (AD) patients with an inherited form of the disease carry mutations in the presenilin proteins (PSEN1; PSEN2) or in the amyloid precursor protein (APP). These disease linked mutations result in increased production of the longer form of amyloid beta (main component of amyloid deposits found in AD brains). Presenilins are postulated to regulate APP processing through their effects on gamma secretase, an enzyme that cleaves APP.