p300 Polyclonal Antibody, 50ul[BT-AP06773] Cell Function Analysis The protein encoded by this

The protein encoded by this gene is a nuclear transcription factor which binds DNA as a homodimer

It phosphorylates the eukaryotic initiation factor 4E (eIF4E)

There is a read-through locus (GeneID: 100526761) that shares sequence identity with this gene and the upstream CCDC169 (GeneID: 728591)

This gene has been found fused to a variety of translocation partner genes in various leukemias

GTPases of the RAB family bind to various effectors to regulate the targeting and fusion of transport carriers to acceptor compartments

p300 Polyclonal Antibody, 50ul[BT-AP06773] Cell Function Analysis The protein encoded by thisEP300 (E1A binding protein p300) encodes the adenovirus E1A associated cellular p300 transcriptional co activator protein. It functions as histone acetyltransferase that regulates transcription via chromatin remodeling and is important in the processes of cell proliferation and differentiation. It mediates cAMP gene regulation by binding specifically to phosphorylated CREB protein. EP300 has also been identified as a co activator of HIF1A (hypoxia