RUNX1(Phospho Ser435) Polyclonal Antibody, 100ul Glassware and multiple polyadenylation sites are

and multiple polyadenylation sites are indicated

The function of this protein has not been determined

This gene is present in a cluster of related genes and pseudogenes on chromosome 12

Belongs to the UPL family

It interacts with the centrosomal proteins aurora-A and ajuba and is required for accumulation of gamma-tubulin and spindle formation at the onset of mitosis

RUNX1(Phospho Ser435) Polyclonal Antibody, 100ul Glassware and multiple polyadenylation sites areCore binding factor (CBF) is a heterodimeric transcription factor that binds to the core element of many enhancers and promoters. The protein encoded by this gene represents the alpha subunit of CBF and is thought to be involved in the development of normal hematopoiesis. Chromosomal translocations involving this gene are well documented and have been associated with several types of leukemia. Three transcript variants encoding different isoforms have