Glucuronidase Beta Polyclonal Antibody, 100ul Cell Culture Plates Unlike the other two isoforms|
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Glucuronidase Beta Polyclonal Antibody, 100ul Cell Culture Plates Unlike the other two isoforms|GUSB encodes a hydrolase that degrades glycosaminoglycans, including heparan sulfate, dermatan sulfate, and chondroitin 4,6 sulfate. The enzyme forms a homotetramer that is localized to the lysosome. Mutations in this gene result in mucopolysaccharidosis type VII. Alternative splicing results in multiple transcript variants. There are many pseudogenes of this locus in the human genome.
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