HSP70L Polyclonal Antibody, 100ul Culture Media thus| it functions as a

thus| it functions as a regulator of a wide variety of downstream proteins| including tumor suppressor proteins p53 and BRCA1| checkpoint kinase CHK2| checkpoint proteins RAD17 and RAD9| and DNA repair protein NBS1

tissue specificity:Ubiquitously expressed at low level

This gene encodes a protein with a tetratricopeptide repeat (TPR) domain containing several TPRs of about 34 aa each

Mutations in TH have been associated with autosomal recessive Segawa syndrome

This gene encodes a member of the Abelson family of nonreceptor tyrosine protein kinases

HSP70L Polyclonal Antibody, 100ul Culture Media thus| it functions as aThis gene encodes a 70kDa heat shock protein. In conjunction with other heat shock proteins, this protein stabilizes existing proteins against aggregation and mediates the folding of newly translated proteins in the cytosol and in organelles. The gene is located in the major histocompatibility complex class III region, in a cluster with two closely related genes which also encode isoforms of the 70kDa heat shock protein.