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Tumor cells activate multiple carcinogenic pathways, leading to increased expression of transporters and metabolism-related enzymes, which in turn results in enhanced uptake of glutamine by tumor cells and massive consumption of glutamine in the TME [7, 23]

It is likely more possible complex of SeNP-MT 13 complex contribute to ROS regulation

Iron exists in almost all cells in the form of stable ferritin and labile iron pools (LIPs), serving as a cofactor or substrate for various proteins involved in critical biological functions, including DNA replication and lipid synthesis