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PEX14 Polyclonal Antibody, 100ul 3D Culture Contains 1 Myb-like domain

SKU: 64196094864

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PEX14 Polyclonal Antibody, 100ul 3D Culture Contains 1 Myb-like domainThis gene encodes an essential component of the peroxisomal import machinery. The protein is integrated into peroxisome membranes with its C terminus exposed to the cytosol, and interacts with the cytosolic receptor for proteins containing a PTS1 peroxisomal targeting signal. The protein also functions as a transcriptional corepressor and interacts with a histone deacetylase. A mutation in this gene results in one form of Zellweger syndrome.

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Description

Contains 1 Myb-like domain

and is involved in the regulation of immune and inflammatory responses

It also interacts with and is phosphoryated by serine/threonine kinase 25

The gene was shown to be expressed primarily in brain and liver| and at a lower level in heart and stomach

Contains 4 copies of a cytoplasmic motif that is referred to as the immunoreceptor tyrosine-based inhibitor motif (ITIM)

PEX14 Polyclonal Antibody, 100ul 3D Culture Contains 1 Myb-like domainThis gene encodes an essential component of the peroxisomal import machinery. The protein is integrated into peroxisome membranes with its C terminus exposed to the cytosol, and interacts with the cytosolic receptor for proteins containing a PTS1 peroxisomal targeting signal. The protein also functions as a transcriptional corepressor and interacts with a histone deacetylase. A mutation in this gene results in one form of Zellweger syndrome.

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