HMG-1 Polyclonal Antibody, 50ul[BT-AP04140] Cellular Cultivation & Health Management extracellular protein with protease inhibitor-like

extracellular protein with protease inhibitor-like domains whose expression is suppressed strongly in many tumors and cells transformed by various kinds of oncogenes

the encoded protein binds to the promoter region of TGFB-responsive genes and recruits a nuclear repressor complex

It is subject to negative-feedback regulation by U-PA which cleaves it into an inactive form

BRSK1 (BR serine/threonine-protein kinase 1)

the encoded protein interacts with LIS1

HMG-1 Polyclonal Antibody, 50ul[BT-AP04140] Cellular Cultivation & Health Management extracellular protein with protease inhibitor-likeHMGB1 encodes high mobility group box 1 that belongs to the High Mobility Group box superfamily. The encoded non histone, nuclear DNA binding protein regulates transcription, and is involved in organization of DNA. This protein plays a role in several cellular processes, including inflammation, cell differentiation and tumor cell migration. Multiple pseudogenes of this gene have been identified. Alternative splicing results in multiple transcript