LAX1 Polyclonal Antibody, 50ul Multiplex Immunoassays MRE11A encodes a nuclear protein

MRE11A encodes a nuclear protein involved in homologous recombination

One of the transcripts produced from this locus

It has higher identity to E2F4 than to other family members

The encoded protein functions through direct interaction with target mRNAs and by disrupting the maturation of certain miRNAs involved in embryonic development

This gene encodes an integral membrane protein of small synaptic vesicles in brain and endocrine cells

LAX1 Polyclonal Antibody, 50ul Multiplex Immunoassays MRE11A encodes a nuclear proteinNegatively regulates TCR (T cell antigen receptor) mediated signaling in T cells and BCR (B cell antigen receptor) mediated signaling in B cells.,induction: Up regulated in T cells following TCR engagement.,PTM: Phosphorylated on tyrosines by Syk, Lck or ZAP70 upon TCR or BCR activation; which leads to the recruitment of GRB2, PIK3R1 and GRAP2.,subunit: When phosphorylated, interacts with GRB2, PIK3R1 and GRAP2.,tissue specificity: Expressed in